Herein, we reviewed our experience with the surgical management of 85 CPA patients in the present study, to evaluate the surgical outcomes of different types of CPA.įrom 2014 to 2020, 85 patients with CPA underwent surgery at Shandong Provincial Chest Hospital in China. What’s more, we have performed surgery for different types of CPA in recent years. We believe that surgery is beneficial for certain CPA patients, no matter what type of CPA. The reported experience mainly focused on simple aspergilloma, few about other types of CPA. Surgery offers a chance of cure, but this is limited to selected patients with localized lesions. Side effects, drug resistance, inevitable recurrence after drug withdrawal, and other problems also come along with them. However, some patients are not sensitive to antifungal therapy and need to use drugs for a long time. Other types of CPA are all first treated by antifungal therapy usually. Treatment for AN differs from clinical symptoms and relevant examinations. SA with symptoms is recommended for surgical treatment, while close follow-up with observation is recommended for asymptomatic SA. CPA is categorised as single (simple) pulmonary aspergilloma (SA), chronic cavitary pulmonary aspergillosis (CCPA), chronic fibrosing pulmonary aspergillosis (CFPA), aspergillus nodule (AN), subacute invasive aspergillosis (SAIA). The European Society for Clinical Microbiology and Infectious Diseases (ESCMID) and the European Respiratory Society (ERS) reached an agreement on the rationale and clinical guidelines for diagnosis and management for CPA in 2015. Recent reports have shown an increased incidence of CPA in recent years. Surgical resection seems safe and effective in the treatment of SA, AN, CCPA with a low complication and recurrence rate, while surgery for CFPA should be limited to selected patients because of its higher complication rate.Ĭhronic pulmonary aspergillosis is a pulmonary infection caused by caused by Aspergillus species. Relapse occurred in 2 SA patients, 3 CCPA, and 1 CFPA, respectively, while none of the AN patients relapsed. The mean time to relapse was 14.8 months (2–30 months) after surgery. 6 patients relapsed after surgery with a recurrence rate of 7.1%. We collected and analyzed the preoperative, perioperative, and postoperative data to evaluate the outcomes of surgical treatment of different types of CPA. The patients were divided into four types, including SA, chronic cavitary pulmonary aspergillosis (CCPA), chronic fibrosing pulmonary aspergillosis (CFPA), aspergillus nodule (AN). We performed a retrospective analysis of 85 patients with CPA who underwent surgery from 2014 to 2020 at Shandong Provincial Chest Hospital. The present study aims to evaluate the outcomes of surgical treatment for different types of CPA. The reported experience of surgical treatment for chronic pulmonary aspergillosis (CPA) mainly focused on simple aspergilloma (SA), few about other types of CPA.
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